Restore Your Gut Health to Remove Depression & Anxiety

Restore Your Gut Health to Remove Depression & Anxiety
by Brad King, MS, MFS

 

Most of us think of the brain as the seat of consciousness, the place where moods are made and behaviors shaped. Feeling anxious? Depressed? We’ve been taught to blame a chemical glitch in the brain’s wiring. It’s the story behind why millions of us swallow pills like Prozac, Zoloft, or Paxil. But here’s the twist: a growing body of science suggests the real action might be happening much farther south—in the gut.

As I put the finishing touches on my new book about the power of the gut, I can assure you: a growing body of science is uncovering a profound—and long overlooked—connection between the health of our digestive system and how we feel, day in and day out. It’s a relationship well worth paying attention to. In many cases, poor gut health isn’t just behind bloating or digestive discomfort; it may be the hidden cause of conditions like anxiety and depression.

Your Gut: Where Neurotransmitters Are Born

Most people don’t realize that nearly 90% of the “feel-good” neurotransmitter serotonin isn’t made in the brain at all—it’s produced in the gut[1]. Likewise, about half of your “motivation and pleasure” chemical, dopamine, also originates in the gut[2]. So, it stands to reason: if your gut isn’t producing enough of these natural antidepressant and anti-anxiety compounds, how on earth will your brain have enough to keep you balanced?

The good news? By nourishing your gut, you’re not just supporting digestion—you’re laying the groundwork for a more resilient, more joyful mind. And it all starts with feeding the trillions of microbes that call your gut home.

The thriving microbial ecosystem that lives within you, is known as your microbiome. These tiny organisms do far more than help digest your meals—they’re actively involved in manufacturing, or nudging the production of, the very neurochemicals that shape your mood, focus, and behavior. anxi

How the Gut Talks to the Brain

Communication between your gut and brain is called the gut-brain axis, a two-way highway that operates through several channels:

  1. The Vagus Nerve: This major nerve acts like a direct phone line between your gut and brain, carrying signals initiated by neurotransmitters and gut bacteria[3].

 

  1. The Circulatory System: The gut doesn’t just produce key neurochemical building blocks—it also generates powerful byproducts of probiotic activity, known as postbiotics, including short-chain fatty acids. These compounds enter the bloodstream and cross the blood-brain barrier, where they can directly influence mental processes like mood, focus, and the stress response[4].
  2. The Immune System: Inflammation in the gut often releases cytokines—molecules that affect brain function and mood, and contribute to depression or anxiety[5].

When the gut microbiome becomes unbalanced—whether due to poor diet, stress, antibiotics, or other factors—these lines of communication fail, which can often leads to various mood disorders.

Restore Gut Health - Boost Brain Health

Fortunately, you have significant control over the health of your gut and, by extension, your mind. Here are my five top ways to strengthen the gut-brain connection:


1. Eat Fiber-Rich, Whole Foods

Diet is the single most influential factor shaping the microbiome. Consuming a variety of fiber-rich foods—vegetables, fruits, nuts, and even prebiotic fiber formulas (more on this below)—feeds beneficial bacteria, supporting diverse microbial communities essential for producing neurotransmitters and reducing inflammation[6].


2. Incorporate Fermented Foods

Foods like yogurt, kefir, kimchi, and sauerkraut contain live bacteria that help replenish gut flora. Adding these regularly can enhance the gut’s diversity and function[7].


3. Supplement with a High Quality Prebiotic Blend

One particularly effective option is Real Bio-Gut Superfood, a 100% organic prebiotic formula designed specifically to feed and diversify the microbiome. It contains (per serving):

·       Brightseed BioGut Fiber (5g): Derived from hemp hulls, rich in bioactives that fuel gut bacteria and stimulate production of beneficial postbiotics, especially butyrate—a short-chain fatty acid linked to reduced inflammation and improved mood[8].

·       Acacia Gum (2g): A gentle prebiotic fiber that nourishes good bacteria without bloating, promoting better digestion and smoother bowel movements[9].

·       Baobab Powder (2g): Packed with fiber and antioxidants, baobab supports microbial diversity and gut barrier integrity[10].

What sets this blend apart is its ability to stimulate postbiotic production—the beneficial compounds (like SCFAs) your gut bacteria create after digesting fiber. These postbiotics are key players in reducing inflammation, improving gut lining strength, and signaling the brain through the vagus nerve[11].


4. Manage Stress

Stress isn’t just a mental phenomenon; it directly affects gut health by altering microbial composition and increasing inflammation. Regular practices like meditation, yoga, or simply spending time outdoors can calm the gut-brain axis[12].


5. Minimize Processed Foods & Sugar

Highly processed foods, especially those loaded with sugar and additives, harm beneficial bacteria and promote gut dysbiosis (bad bacterial overgrowth). Prioritize whole, minimally processed options to maintain microbial balance[13].


Closing Thought

For too long, we’ve separated the health of the body from the health of the mind. But the gut microbiome sits at the intersection of both. It’s the bridge where digestion, immunity, mood, and cognitive clarity meet.

Supporting your gut isn’t just about avoiding stomach troubles. It’s about nurturing the unseen ecosystem that shapes how you feel, think, and live. The next time you’re tempted to brush off your digestion, remember: a well-fed gut often leads to a well-fed mind.


References:



[1] Gershon, M.D. (1998). The Second Brain: A Groundbreaking New Understanding of Nervous Disorders of the Stomach and Intestine.

[2] Strandwitz, P. (2018). Neurotransmitter modulation by the gut microbiota. Brain Research, 1693, 128-133.

[3] Breit, S., Kupferberg, A., Rogler, G., & Hasler, G. (2018). Vagus nerve as modulator of the brain–gut axis in psychiatric and inflammatory disorders. Frontiers in Psychiatry, 9, 44.

[4] Dalile, B., Van Oudenhove, L., Vervliet, B., & Verbeke, K. (2019). The role of short-chain fatty acids in microbiota–gut–brain communication. Nature Reviews Gastroenterology & Hepatology, 16(8), 461-478.

[5] Maes, M., Kubera, M., & Leunis, J.C. (2008). The gut-brain barrier in major depression: intestinal mucosal dysfunction with an increased translocation of LPS from gram-negative enterobacteria (leaky gut). Neuro Endocrinology Letters, 29(1), 117-124.

[6] De Filippo, C. et al. (2010). Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. PNAS, 107(33), 14691-14696.

[7] Marco, M.L., et al. (2017). Health benefits of fermented foods: microbiota and beyond. Current Opinion in Biotechnology, 44, 94-102.

[8] Brightseed BioGut Fiber: Brightseed. (2023). Bio Gut Fiber. Brightseedbio.com. https://www.brightseedbio.com/bioactives/bio-gut-fiber

[9] Babiker, R., et al. (2023). Effect of gum Arabic (Acacia senegal) supplementation on the gut microbiota and intestinal barrier function in mice. Nutrients, 15(1), 173. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10624802/

[10] Coe, S. A., Clegg, M., Armengol, M., & Ryan, L. (2013). The polyphenol-rich baobab fruit (Adansonia digitata L.) reduces starch digestion and glycemic response in humans. Nutrition Research, 33(11), 888–896. https://doi.org/10.1016/j.nutres.2013.07.002

[11] Parada Venegas, D., et al. (2019). Short Chain Fatty Acids (SCFAs)-mediated gut epithelial and immune regulation and its relevance for inflammatory bowel diseases. Frontiers in Immunology, 10, 277.

[12] Foster, J.A., & Neufeld, K.A.M. (2013). Gut–brain axis: how the microbiome influences anxiety and depression. Trends in Neurosciences, 36(5), 305-312.

[13] Sonnenburg, E.D., & Sonnenburg, J.L. (2019). The ancestral and industrialized gut microbiota and implications for human health. Nature Reviews Microbiology, 17(6), 383-390.

 


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